2741 Phospho-MARCKS (Ser152/156) Antibody #2741

"上海博耀生物销售Phospho-MARCKS (Ser152/156) Antibody #2741，CST原装品质，价格优惠，订购Phospho-MARCKS (Ser152/156) Anti

"上海博耀生物销售Phospho-MARCKS (Ser152/156) Antibody #2741，CST原装品质，价格优惠，订购Phospho-MARCKS (Ser152/156) Antibody #2741，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-MARCKS (Ser152/156) Antibody #2741
货号：2741
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2741S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R	Endogenous	75 mouse, rat. 80 human.	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-MARCKS (Ser152/156) Antibody detects endogenous levels of MARCKS only when phosphorylated at serines 152 and 156 .
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser152/156 of rat MARCKS. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) is a major PKC substrate expressed in many cell types. MARCKS has been implicated in cell motility, cell adhesion, phagocytosis, membrane traffic, and mitogenesis (1). PKC phosphorylates Ser159, 163, 167, and 170 of MARCKS in response to growth factors and oxidative stress. Phosphorylation at these sites regulates the calcium/calmodulin binding and filamentous (F)-actin cross-linking activities of MARCKS (2-4). Phosphorylation by PKC also results in translocation of MARCKS from the plasma membrane to the cytoplasm (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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