2735 XRCC1 Antibody #2735

"上海博耀生物销售XRCC1 Antibody #2735，CST原装品质，价格优惠，订购XRCC1 Antibody #2735，详情请咨询销售人员！产品详细参数

"上海博耀生物销售XRCC1 Antibody #2735，CST原装品质，价格优惠，订购XRCC1 Antibody #2735，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：XRCC1 Antibody #2735
货号：2735
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2735S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP IF-IC	H (Mk)	Endogenous	82	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： XRCC1 Antibody detects endogenous levels of total XRCC1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acids surrounding Arg300 of human XRCC1. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The X-ray repair cross complementing protein 1 (XRCC1) is a DNA repair protein important in both single strand break repair and base excision repair following damage from ionizing radiation and alkylating agents (1). XRCC1 acts as a scaffold protein to coordinate DNA abasic site repair through interaction with several other repair proteins (2). At least eight XRCC1 protein partners have been identified, including the polynucleotide kinase PNK (3), DNA ligase III (4,5), poly (ADP-ribose) polymerase (6), and PCNA (7). Mutations and polymorphisms in the XRCC1 gene serve as diagnostic markers and are associated with elevated risk of various forms of cancers (8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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