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2723 Hip Antibody #2723

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2723

更新时间:2013-07-27

浏览次数:683

公司地址:

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产品简介

"上海博耀生物销售Hip Antibody #2723,CST原装品质,价格优惠,订购Hip Antibody #2723,详情请咨询销售人员!产品详细参数如下

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"上海博耀生物销售Hip Antibody #2723,CST原装品质,价格优惠,订购Hip Antibody #2723,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Hip Antibody #2723
货号:2723
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
2723S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W H M R Mk Endogenous 48 Rabbit
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Hip Antibody detects endogenous levels of total Hip protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human Hip. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:

Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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