2682 IKKα Antibody #2682

"上海博耀生物销售IKKα Antibody #2682，CST原装品质，价格优惠，订购IKKα Antibody #2682，详情请咨询销售人员！产品详细参数

"上海博耀生物销售IKKα Antibody #2682，CST原装品质，价格优惠，订购IKKα Antibody #2682，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：IKKα Antibody #2682
货号：2682
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2682P	40 ul (4 western blots)	询价
2682S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H M R Mk (B)	Endogenous	85	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： IKKα Antibody detects endogenous levels of total IKKα protein. The antibody does not cross-react with IKKβ or IKKγ.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the 20 amino-terminal residues of human IKKα. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The NF-κB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IκB proteins (1-3). Most agents that activate NF-κB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IκB (3-7). The key regulatory step in this pathway involves activation of a high molecular weight IκB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits. IKKα and IKKβ serve as the catalytic subunits of the kinase and IKKγ serves as the regulatory subunit (8,9). Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKβ (Ser176 and Ser180 in IKKα), which causes conformational changes, resulting in kinase activation (10-13).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-Fascin1纤维束1抗体
Anti-PHD3脯氨酸羟化酶抗体
ab103910/Anti-ETFDH antibody
Anti-presenilin 1/PS-1早老素蛋白-1抗体
Anti-Secretin receptor分泌素受体抗体
ab102561/Anti-C17orf75 antibody
Anti-DR3/APO3/TWEAK死亡受体3抗体
ab103971/Anti-FAM161A antibody
Anti-T3三碘甲狀腺素T3抗体
ab101892/Anti-CATSPER4 antibody
Anti-NRP1/CD304神经纤毛蛋白1抗体
Anti-VAP1血管粘附蛋白1抗体
ab103483/Anti-C21orf128 antibody
ab100927/Anti-DUSP22 antibody
ab101359/Anti-CTTNBP2NL antibody
ab103549/Anti-Angiotensinogen antibody"
本页产品地址：http://www.geilan.com/sell/show-3243749.html