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2679 Calnexin (C5C9) Rabbit mAb #2679

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2679

更新时间:2013-07-27

浏览次数:712

公司地址:

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产品简介

"上海博耀生物销售Calnexin (C5C9) Rabbit mAb #2679,CST原装品质,价格优惠,订购Calnexin (C5C9) Rabbit mAb #2679,详情请咨

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"上海博耀生物销售Calnexin (C5C9) Rabbit mAb #2679,CST原装品质,价格优惠,订购Calnexin (C5C9) Rabbit mAb #2679,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Calnexin (C5C9) Rabbit mAb #2679
货号:2679
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Calnexin
规格:
No. Size Price
2679P 40 ul (4 western blots) 询价
2679S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Isotype
W IHC-P IF-IC H Mk Endogenous 90 Rabbit
Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Calnexin (C5C9) Rabbit mAb detects endogenous levels of total calnexin protein.
来源及纯化方法: Calnexin (C5C9) Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human calnexin.
抗体背景:

Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. Calnexin was first identified as being involved in the assembly of murine class I histocompatibility molecules (1,2). Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control (3-5). The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide intermediate on the folding glycoprotein (5).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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