产品简介
"上海博耀生物销售Calnexin (C5C9) Rabbit mAb #2679,CST原装品质,价格优惠,订购Calnexin (C5C9) Rabbit mAb #2679,详情请咨
产品说明
"上海博耀生物销售
Calnexin (C5C9) Rabbit mAb #2679,CST原装品质,价格优惠,订购
Calnexin (C5C9) Rabbit mAb #2679,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:Calnexin (C5C9) Rabbit mAb #2679
货号:2679
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Calnexin
规格:
| No. |
Size |
Price |
| 2679P |
40 ul (4 western blots) |
询价 |
| 2679S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Isotype |
| W IHC-P IF-IC |
H Mk |
Endogenous |
90 |
Rabbit |
Applications Key:
W=Western Blotting
IHC-P=Immunohistochemistry (Paraffin)
IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:
H=Human
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
Calnexin (C5C9) Rabbit mAb detects endogenous levels of total calnexin protein.
来源及纯化方法:
Calnexin (C5C9) Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human calnexin.
抗体背景:
Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. Calnexin was first identified as being involved in the assembly of murine class I histocompatibility molecules (1,2). Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control (3-5). The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide intermediate on the folding glycoprotein (5).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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