2663 Deltex-2 Antibody #2663

"上海博耀生物销售Deltex-2 Antibody #2663，CST原装品质，价格优惠，订购Deltex-2 Antibody #2663，详情请咨询销售人员！产品详

"上海博耀生物销售Deltex-2 Antibody #2663，CST原装品质，价格优惠，订购Deltex-2 Antibody #2663，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Deltex-2 Antibody #2663
货号：2663
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2663S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	M (H) (R)	Transfected Only	70	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Deltex-2 Antibody detects transfected levels of total Deltex-2 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala607 of human Deltex-2. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Deltex (DTX) encodes a putative E3 ubiquitin ligase first identified from Drosophila and shown to modulate Notch signaling (1). Several mammalian Deltex homologs have been isolated (2,3), all containing a pair of WWE repeats, a proline-rich region, and a Ring-finger domain (4,5). Deltex binds to the ankyrin-repeat domain of Notch and is capable of regulating Notch signaling positively or negatively in different systems (4,6). In addition, Deltex can also form homo-multimers (4). While Deltex has been implicated in Notch signaling regulation of lymphocyte development, this signal modifier may also have a transcriptional function independent of Notch (3, 6-8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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