2659 Emerin (L12) Antibody #2659

"上海博耀生物销售Emerin (L12) Antibody #2659，CST原装品质，价格优惠，订购Emerin (L12) Antibody #2659，详情请咨询销售人员

"上海博耀生物销售Emerin (L12) Antibody #2659，CST原装品质，价格优惠，订购Emerin (L12) Antibody #2659，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Emerin (L12) Antibody #2659
货号：2659
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2659S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H	Endogenous	30	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Emerin (L12) Antibody detects endogenous levels of total Emerin protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu12 of human Emerin. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Emerin is a broadly expressed integral protein of the nuclear inner membrane (1). It contains a LEM domain and binds to several nuclear proteins, such as BAF (barrier-to-autointegration factor) and A- and B-type lamins, which are important in nuclear functions (2-5). Emerin may regulate gene expression through binding to other transcriptional regulators (6,7). Emerin binds to β-catenin and inhibits its nuclear accumulation (8). Recent studies demonstrate that Emerin is required for HIV-1 infectivity (9). Mutations in Emerin are a major cause of Emery-Dreifuss muscular dystrophy (EDMD), a disorder characterized by progressive skeletal muscle weakening (10).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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