2645 Trf2 Antibody #2645

"上海博耀生物销售Trf2 Antibody #2645，CST原装品质，价格优惠，订购Trf2 Antibody #2645，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售Trf2 Antibody #2645，CST原装品质，价格优惠，订购Trf2 Antibody #2645，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Trf2 Antibody #2645
货号：2645
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2645S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H Mk	Endogenous	65	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Trf2 Antibody detects endogenous levels of Trf2 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide correspoding to residues near the carboxy terminus of human Trf2. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Telomeres, the linear ends of chromosomes, are organized into T-loops to prevent them from being recognized by the cell as DNA double stranded breaks (DSBs) (1). The telomeric repeat binding factor proteins, Trf1 and Trf2, bind to double-stranded telomeres, allowing formation of T-loops (2). A large number of proteins involved in the DNA damage response are found present within telomeres physically associated with Trf2 (3). Interestingly, Trf2 can be observed to transiently localize to DNA damage-induced DSBs, but overexpression of Trf2 prevents ATM-dependent signaling (4). Phosphorylation of Trf2 at Ser323 has been reported in vivo, but no upstream kinase or role has been established for this phosphorylation site (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-Connexin-40间隙连接蛋白40抗体
Anti-SM-MHC心肌肌球蛋白抗体（α-myosin）
ab10060/Anti-Ferritin, mitochondrial antibody
ab101699/Anti-Ephrin B3 antibody
Anti-Cadherin 8钙粘附蛋白8抗体
Anti-CDKN1B/P27kip1P27抗体/周期素依赖激酶抑制剂
Anti-DLX4DLX4抗体
Anti-ZNF231/Bassoon锌指蛋白231抗体
Anti-Nm23/NME1/NME2肿瘤转移抑制基因抗体
Anti-Caspase-6 (NT)半胱胺酸蛋白酶蛋白-6抗体(N端)
ab102755/Anti-CSPP1 antibody
Anti-ZCWCC1ZCWCC1抗体
ab10054/Anti-D-Dimer antibody
ab103673/Anti-ATF6 beta antibody
ab10369/Anti-Eotaxin antibody
Anti-Tyrosine Hydroxylase(Neuronal Marker)/Tyk2/TYH酪氨酸羟化酶抗体"
本页产品地址：http://www.geilan.com/sell/show-3243706.html