2643 GLI1 (L42B10) Mouse mAb #2643

"上海博耀生物销售GLI1 (L42B10) Mouse mAb #2643，CST原装品质，价格优惠，订购GLI1 (L42B10) Mouse mAb #2643，详情请咨询销售

"上海博耀生物销售GLI1 (L42B10) Mouse mAb #2643，CST原装品质，价格优惠，订购GLI1 (L42B10) Mouse mAb #2643，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：GLI1 (L42B10) Mouse mAb #2643
货号：2643
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2643S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP	H	Endogenous	160	Mouse IgG1

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： GLI1 (L42B10) Mouse mAb detects endogenous levels of total GLI1 protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a recombinant human GLI1 protein.
抗体背景：

GLI was first identified as a gene amplified in a malignant glioma (1) capable of transforming primary cells in cooperation with adenovirus E1A (2). GLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3 (3). These GLI proteins are similar to the Drosophila homolog Cubitus interruptus (Ci) and function as transcription factors activated by the Hedgehog signaling pathway. Hedgehog signaling plays an important role in animal development, and research studies have shown that this pathway is aberrantly activated in many types of cancers (4,5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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