2639 Fibrillarin (C13C3) Rabbit mAb #2639

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"上海博耀生物销售Fibrillarin (C13C3) Rabbit mAb #2639，CST原装品质，价格优惠，订购Fibrillarin (C13C3) Rabbit mAb #2639，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Fibrillarin (C13C3) Rabbit mAb #2639
货号：2639
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2639P	40 ul (4 western blots)	询价
2639S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IF-IC	H M R Mk	Endogenous	37	Rabbit IgG

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Fibrillarin (C13C3) Rabbit mAb detects endogenous levels of total fibrillarin protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide surrounding Thr298 of human fibrillarin.
抗体背景：

Fibrillarin is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place (1,2). Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence (3,4). The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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