2637 BTAF1 Antibody #2637

"上海博耀生物销售BTAF1 Antibody #2637，CST原装品质，价格优惠，订购BTAF1 Antibody #2637，详情请咨询销售人员！产品详细参数

"上海博耀生物销售BTAF1 Antibody #2637，CST原装品质，价格优惠，订购BTAF1 Antibody #2637，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：BTAF1 Antibody #2637
货号：2637
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2637S	100 ul	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H M R Mk (Hm) (B) (Hr)	Endogenous	200	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Hm=Hamster  Mk=Mon key  B=Bovine  Hr=Horse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： BTAF1 Antibody recognizes endogenous levels of total BTAF1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala220 of human BTAF1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

B-TATA binding protein-associated factor 1 (BTAF1) is a human homolog of the yeast protein modifier of transcription 1 (MOT1) (1). BTAF1 negatively regulates transcription through interaction with TATA binding protein (TBP), an important component of the B-TFIID complex (2,3). BTAF1 is a member of the SNF2 family of ATPases that utilizes ATP to remove TBP from B-TFIID, thereby preventing formation of the transcription pre-initiation complex (PIC) (3-5). BTAF1 actively removes TBP from DNA, which prevents non-specific TBP-DNA interactions and promotes disassembly of inactive forms of the PIC. This activity is thought to be critical for maintaining a pool of free TBP that is necessary for the assembly of the PIC during transcription activation (6,7).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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