2633 Toll-like Receptor 7 Antibody #2633

"上海博耀生物销售Toll-like Receptor 7 Antibody #2633，CST原装品质，价格优惠，订购Toll-like Receptor 7 Antibody #2633，详

"上海博耀生物销售Toll-like Receptor 7 Antibody #2633，CST原装品质，价格优惠，订购Toll-like Receptor 7 Antibody #2633，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Toll-like Receptor 7 Antibody #2633
货号：2633
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2633P	40 ul (4 western blots)	询价
2633S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R (Mk) (Dg)	Endogenous	140	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  Dg=Dog
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Toll-like Receptor 7 Antibody detects endogenous levels of total TLR7 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxyl terminus of TLR7 protein. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the Toll/Interleukin-1 receptor (TIR) domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains, including myeloid differentiation factor 88 (MyD88), MyD88-adaptor-like/TIR-associated protein (MAL/TIRAP), Toll-receptor-associated activator of interferon (TRIF), and Toll-receptor-associated molecule (TRAM). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IκB, which normally maintains NF-κB in an inactive state by sequestering it in the cytoplasm.

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-Phospho-CBX5(Tyr37)磷酸化CBX5抗体
ab103703/Anti-FAM169A antibody
ab10028/Anti-C Reactive Protein antibody
Anti-GLUT4葡萄糖转运蛋白4抗体
Anti-Neurofascin/Nfasc155神经束蛋白155抗体
ab101886/Anti-GRID2 antibody
Anti-SYK非受体型酪氨酸蛋白激酶抗体
ab101855/Anti-BASP1 antibody
ab101555/Anti-ACBD6 antibody
Anti-HSP60热休克蛋白-60抗体
Anti-MOG髓鞘少树突胶质细胞糖蛋白抗体
Anti-TRA16睾丸激素孤儿受体相关蛋白抗体
Anti-CSIG细胞衰老抑制基因抗体
ab101681/Anti-Alas1 antibody
ab104110/Anti-ATP1B4 antibody
Anti-ADRB1肾上腺素能受体β1抗体"
本页产品地址：http://www.geilan.com/sell/show-3243691.html