2585 GLI2 (R770) Antibody #2585

"上海博耀生物销售GLI2 (R770) Antibody #2585，CST原装品质，价格优惠，订购GLI2 (R770) Antibody #2585，详情请咨询销售人员！

"上海博耀生物销售GLI2 (R770) Antibody #2585，CST原装品质，价格优惠，订购GLI2 (R770) Antibody #2585，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：GLI2 (R770) Antibody #2585
货号：2585
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2585S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H	Transfected Only	220	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： GLI2 (R770) Antibody detects transfected levels of human GLI2 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg770 of human GLI2. Antibodies are purified by peptide affinity chromatography.
抗体背景：

GLI was first identified as a gene amplified in a malignant glioma (1) capable of transforming primary cells in cooperation with adenovirus E1A (2). GLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3 (3). These GLI proteins are similar to the Drosophila homolog Cubitus interruptus (Ci) and function as transcription factors activated by the Hedgehog signaling pathway. Hedgehog signaling plays an important role in animal development, and research studies have shown that this pathway is aberrantly activated in many types of cancers (4,5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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