2581 Phospho-PP1α (Thr320) Antibody #2581

"上海博耀生物销售Phospho-PP1α (Thr320) Antibody #2581，CST原装品质，价格优惠，订购Phospho-PP1α (Thr320) Antibody #2581

"上海博耀生物销售Phospho-PP1α (Thr320) Antibody #2581，CST原装品质，价格优惠，订购Phospho-PP1α (Thr320) Antibody #2581，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-PP1α (Thr320) Antibody #2581
货号：2581
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2581S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IHC-P	H M R Mk	Endogenous	38	Rabbit

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-PP1α (Thr320) Antibody detects PP1α only when phosphorylated at Thr320. This antibody may cross-react with the phosphorylated δ or γ isoforms of PP1.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr320 of human PP1α. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1α, PP1δ, PP1γ1 and PP1γ2 (1). Involvement in cell cycle regulation is one of the biological functions of PP1 (1). It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis (2,3). A cell cycle-dependent phosphorylation at Thr320 of PP1α by cdc2 kinase inhibits PP1α activity (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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