2573 Heregulin Antibody #2573

"上海博耀生物销售Heregulin Antibody #2573，CST原装品质，价格优惠，订购Heregulin Antibody #2573，详情请咨询销售人员！产品

"上海博耀生物销售Heregulin Antibody #2573，CST原装品质，价格优惠，订购Heregulin Antibody #2573，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Heregulin Antibody #2573
货号：2573
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2573S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M	Endogenous	105	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Heregulin Antibody detects endogenous levels of total heregulin proteins. The antibody does not cross-react with other family members.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His494 of human heregulin. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Heregulin (HRG), also called neuregulin (NRG1), neu differentiation factor (NDF) or glial growth factor-2 (GGF-2), is a soluble growth factor synthesized as a transmembrane precursor molecule. Metalloproteinases and other proteases catalyze the cleavage of its extracellular domain which is then released and functions as a ligand for ErbB3 and ErbB4 receptor tyrosine kinase. The signaling pathways of HRG-ErbB3/ErbB4 are involved in regulation of cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues (1,2). Abnormality of HRG-ErbB signaling leads to development of a variety of human diseases.HRG family has four isoforms including HRG-1, -2, -3 and -4, which are derived from alternative exon splicing. Moreover, they showed various tissue expression and biological activities (3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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