2548 EDC4/Ge-1 Antibody #2548

"上海博耀生物销售EDC4/Ge-1 Antibody #2548，CST原装品质，价格优惠，订购EDC4/Ge-1 Antibody #2548，详情请咨询销售人员！产品

"上海博耀生物销售EDC4/Ge-1 Antibody #2548，CST原装品质，价格优惠，订购EDC4/Ge-1 Antibody #2548，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：EDC4/Ge-1 Antibody #2548
货号：2548
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2548S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP IF-IC	H M Mk	Endogenous	170	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： EDC4/Ge-1 Antibody detects endogenous levels of total EDC4/Ge-1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human EDC4/Ge-1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sjögren's syndrome patient later diagnosed with primary biliary cirrhosis (1). EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation (2). Identified EDC4 protein is found as a pair of isoforms generated by alternative splicing and contains several WD domains and a putative nuclear localization signal. EDC4 co-localizes with other P-body decapping proteins such as DCP1A, DCP2 and GW182 (2,3). Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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