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2530 Wnt5a/b (C27E8) Rabbit mAb #2530

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2530

更新时间:2013-07-27

浏览次数:838

公司地址:

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产品简介

"上海博耀生物销售Wnt5a/b (C27E8) Rabbit mAb #2530,CST原装品质,价格优惠,订购Wnt5a/b (C27E8) Rabbit mAb #2530,详情请咨

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"上海博耀生物销售Wnt5a/b (C27E8) Rabbit mAb #2530,CST原装品质,价格优惠,订购Wnt5a/b (C27E8) Rabbit mAb #2530,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Wnt5a/b (C27E8) Rabbit mAb #2530
货号:2530
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Monoclonal
规格:
No. Size Price
2530P 40 ul (4 western blots) 询价
2530S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Isotype
W H M Endogenous 45 Rabbit IgG
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Wnt5a/b (C27E8) Rabbit mAb detects endogenous levels of Wnt5a and Wnt5b proteins. This antibody cross-reacts with an unidentified protein between 55 and 60 kDa.
来源及纯化方法: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu201 of Isoform 1 and Glu186 of Isoform 2 of the human Wnt5a protein. This antibody works to detect both isoforms of human Wnt5a protein.
抗体背景:

The Wnt family includes several secreted glycoproteins that play important roles in animal development (1). There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins (2). Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways (3). The canonical Wnt/β-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family (4). Aberrant activation of Wnt signaling pathways is involved in several types of cancers (5).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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