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2509 AP-2β Antibody #2509

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2509

更新时间:2013-07-27

浏览次数:783

公司地址:

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产品简介

"上海博耀生物销售AP-2β Antibody #2509,CST原装品质,价格优惠,订购AP-2β Antibody #2509,详情请咨询销售人员!产品详细参

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"上海博耀生物销售AP-2β Antibody #2509,CST原装品质,价格优惠,订购AP-2β Antibody #2509,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:AP-2β Antibody #2509
货号:2509
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
2509S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W IP IF-IC H M R Endogenous 49 Rabbit
Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: AP-2β Antibody detects endogenous levels of total AP-2β protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human AP-2β. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:

The sequence-specific transcription factor activator protein 2β (AP-2β) is required for normal kidney development (1). AP-2β knockout mice die 1-2 days after birth due to polycystic kidney disease (1). Massive apoptosis occured during kidney deveopment at the end of embryogenesis in these mice (1). Overexpressed AP-2β has been to found to suppress c-myc-induced apoptosis, indicating a role of this transcription factor in cell survival (1). In addition, overexpression of AP-2β is shown to be related to impaired insulin signaling in adipocytes, and is therefore proposed to be a candidate gene that may relate to obesity (2).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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