产品简介
"上海博耀生物销售AP-2β Antibody #2509,CST原装品质,价格优惠,订购AP-2β Antibody #2509,详情请咨询销售人员!产品详细参
产品说明
"上海博耀生物销售
AP-2β Antibody #2509,CST原装品质,价格优惠,订购
AP-2β Antibody #2509,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:AP-2β Antibody #2509
货号:2509
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2509S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W IP IF-IC |
H M R |
Endogenous |
49 |
Rabbit |
Applications Key:
W=Western Blotting
IP=Immunoprecipitation
IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:
H=Human
M=Mouse
R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
AP-2β Antibody detects endogenous levels of total AP-2β protein.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human AP-2β. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:
The sequence-specific transcription factor activator protein 2β (AP-2β) is required for normal kidney development (1). AP-2β knockout mice die 1-2 days after birth due to polycystic kidney disease (1). Massive apoptosis occured during kidney deveopment at the end of embryogenesis in these mice (1). Overexpressed AP-2β has been to found to suppress c-myc-induced apoptosis, indicating a role of this transcription factor in cell survival (1). In addition, overexpression of AP-2β is shown to be related to impaired insulin signaling in adipocytes, and is therefore proposed to be a candidate gene that may relate to obesity (2).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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