2502 Vav1 Antibody #2502

"上海博耀生物销售Vav1 Antibody #2502，CST原装品质，价格优惠，订购Vav1 Antibody #2502，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售Vav1 Antibody #2502，CST原装品质，价格优惠，订购Vav1 Antibody #2502，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Vav1 Antibody #2502
货号：2502
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2502S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W F	H M R	Endogenous	95	Rabbit

Applications Key:  W=Western Blotting  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Vav Antibody detects endogenous levels of total Vav1 protein. The antibody does not cross-react with Vav2, Vav3 or CelVav.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr174 of human Vav. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian Vav proteins (Vav1, Vav2 and Vav3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. Vav2 and Vav3 are more ubiquitously expressed. Vav proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization (reviewed in 1). Phosphorylation stimulates the GEF activity of Vav protein towards Rho/Rac (2,3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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