2472 VEGF Receptor 2 Antibody #2472

"上海博耀生物销售VEGF Receptor 2 Antibody #2472，CST原装品质，价格优惠，订购VEGF Receptor 2 Antibody #2472，详情请咨询销

"上海博耀生物销售VEGF Receptor 2 Antibody #2472，CST原装品质，价格优惠，订购VEGF Receptor 2 Antibody #2472，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：VEGF Receptor 2 Antibody #2472
货号：2472
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2472S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M (R)	Endogenous	210, 230	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： VEGF Receptor 2 Antibody detects endogenous levels of VEGF-2 receptors. It does not cross-react with other members of VEGF receptor family .
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy-terminal sequence of human VEGF receptor 2. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Vascular endothelial growth factor receptor 2 (VEGFR2, KDR, Flk-1) is a major receptor for VEGF-induced signaling in endothelial cells. Upon ligand binding, VEGFR2 undergoes autophosphorylation and becomes activated (1). Major autophosphorylation sites of VEGFR2 are located in the kinase insert domain (Tyr951/996) and in the tyrosine kinase catalytic domain (Tyr1054/1059) (2). Activation of the receptor leads to rapid recruitment of adaptor proteins, including Shc, GRB2, PI3 kinase, NCK, and the protein tyrosine phosphatases SHP-1 and SHP-2 (3). Phosphorylation at Tyr1212 provides a docking site for GRB2 binding and phospho-Tyr1175 binds the p85 subunit of PI3 kinase and PLCγ, as well as Shb (1,4,5). Signaling from VEGFR2 is necessary for the execution of VEGF-stimulated proliferation, chemotaxis and sprouting, as well as survival of cultured endothelial cells in vitro and angiogenesis in vivo (6-8).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab103896/Anti-ALDH1B1 antibody
Anti-ER-Alpha雌激素受体α抗体（用于western blot）
ab103697/Anti-EPC2 antibody
ab101542/Anti-Cytokeratin 18 antibody
Anti-CHRNA4烟碱型乙酰胆碱受体α4抗体
Anti-IFITM1/CD225干扰素诱导跨膜蛋白1抗体
ab100906/Anti-ACTRT2 antibody
ab101659/Anti-FPR1 antibody
ab10068/Anti-Fibrinogen antibody
ab103088/Anti-C15orf52 antibody
ab10346/Anti-AKAP12 antibody
Anti-factor VIII(FVIII) human第八因子相关抗原抗体
Anti-phospho-NFKB p65(Ser536)磷酸化细胞核因子抗体
Anti-NPY/Neuropeptide Y神经肽Y抗体
ab103153/Anti-Chemerin antibody
Anti-CREB-1环腺苷酸应答元件结合蛋白抗体"
本页产品地址：http://www.geilan.com/sell/show-3242657.html