2466 Cdc42 (11A11) Rabbit mAb #2466

"上海博耀生物销售Cdc42 (11A11) Rabbit mAb #2466，CST原装品质，价格优惠，订购Cdc42 (11A11) Rabbit mAb #2466，详情请咨询销

"上海博耀生物销售Cdc42 (11A11) Rabbit mAb #2466，CST原装品质，价格优惠，订购Cdc42 (11A11) Rabbit mAb #2466，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Cdc42 (11A11) Rabbit mAb #2466
货号：2466
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2466P	40 ul (4 western blots)	询价
2466S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H M R B (X)	Endogenous	21	Rabbit IgG

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  X=Xenopus  B=Bovine
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Cdc42 (11A11) Rabbit mAb detects endogenous levels of total Cdc42 protein. The antibody does not cross-react with other small GTPases.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys135 of human Cdc42.
抗体背景：

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development (1). GTP binding stimulates the activity of Rac/Cdc42, and the hydrolysis of GTP to GDP through the protein's intrinsic GTPase activity, rendering it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs). Another level of regulation is achieved through the binding of RhoGDI, a guanine nucleotide dissociation inhibitor, which retains Rho family GTPases, including Rac and Cdc42, in their inactive GDP-bound state (2,3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-PLGF/PIGF (human)胎盘生长相关抗体（人）
ab100839/Anti-C17orf71 antibody
Anti-Insulin Receptor alpha胰岛素受体α抗体
ab101427/Anti-ERM / Etv5 antibody
Anti-C PeptideC-肽抗体
ab103943/Anti-DHRS2 antibody
ab103676/Anti-ARVCF antibody
Anti-BGP/Osteocalcin骨保护蛋白/骨钙素抗体
ab101143/Anti-ADAM5 antibody
Anti-GAD65谷氨酸脱羧酶-65抗体
ab10370/Anti-Eotaxin 2 antibody
Anti-Collagen VⅤ型胶原抗体
Anti-CD105/EndoglinCD105抗体
Anti-AQP4水通道蛋白-4抗体
Anti-ILVBL乙酰乳酸合成酶蛋白抗体
Anti-NF-M/Neurofilament M中分子量神经丝蛋白抗体"
本页产品地址：http://www.geilan.com/sell/show-3242640.html