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2437 Pdx1 Antibody #2437

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2437

更新时间:2013-07-27

浏览次数:750

公司地址:

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产品简介

"上海博耀生物销售Pdx1 Antibody #2437,CST原装品质,价格优惠,订购Pdx1 Antibody #2437,详情请咨询销售人员!产品详细参数如

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"上海博耀生物销售Pdx1 Antibody #2437,CST原装品质,价格优惠,订购Pdx1 Antibody #2437,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Pdx1 Antibody #2437
货号:2437
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
2437S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W M R (H) Endogenous 42 Rabbit
Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-F=Immunofluorescence (Frozen)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Pdx1 Antibody detects endogenous levels of total Pdx1 protein.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human Pdx1. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:

The pancreatic duodenal homeobox gene-1 (Pdx1) is a transcription factor that contributes to pancreas development, pancreatic β-cell differentiation, and mature β-cell function (1,2). It plays an essential role in the commitment of endoderm to a pancreatic and later β-cell phenotype (2,3). In the mature pancreas, Pdx1 expression is more restricted to the pancreatic β-cells (3), where it promotes the expression of genes important for β-cell functions such as insulin, glucokinase, and Glut2 (4-6). Mutations of the corresponding Pdx1 gene may be associated with diabetes and cases of pancreatic insufficiency (7).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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