2433 Calnexin Antibody #2433

"上海博耀生物销售Calnexin Antibody #2433，CST原装品质，价格优惠，订购Calnexin Antibody #2433，详情请咨询销售人员！产品详

"上海博耀生物销售Calnexin Antibody #2433，CST原装品质，价格优惠，订购Calnexin Antibody #2433，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Calnexin Antibody #2433
货号：2433
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2433S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IHC-P IF-IC	H	Endogenous	90	Rabbit

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Calnexin Antibody detects endogenous levels of total calnexin protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to a sequence around Ala51 of human calnexin. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. Calnexin was first identified as being involved in the assembly of murine class I histocompatibility molecules (1,2). Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control (3-5). The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide intermediate on the folding glycoprotein (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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