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2429 Thioredoxin 1 (C63C6) Rabbit mAb #2429

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2429

更新时间:2013-07-27

浏览次数:761

公司地址:

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产品简介

"上海博耀生物销售Thioredoxin 1 (C63C6) Rabbit mAb #2429,CST原装品质,价格优惠,订购Thioredoxin 1 (C63C6) Rabbit mAb #24

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"上海博耀生物销售Thioredoxin 1 (C63C6) Rabbit mAb #2429,CST原装品质,价格优惠,订购Thioredoxin 1 (C63C6) Rabbit mAb #2429,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Thioredoxin 1 (C63C6) Rabbit mAb #2429
货号:2429
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Thioredoxin
规格:
No. Size Price
2429S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Isotype
W IHC-P H M R Endogenous 12 Rabbit IgG
Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Thioredoxin 1 (C63C6) Rabbit mAb detects endogenous levels of total thioredoxin 1 protein.
来源及纯化方法: Thioredoxin 1 (C63C6) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide corresponding to residues surrounding Ala9 of human thioredoxin 1.
抗体背景:

Thioredoxin is a small redox protein found in many eukaryotes and prokaryotes. A pair of cysteines within a highly conserved, active site sequence can be oxidized to form a disulfide bond which is then reduced by thioredoxin reductase (1). Multiple forms of thioredoxin have been identified, including cytosolic thioredoxin 1 (Trx1) and mitochondrial thioredoxin 2 (Trx2). Thioredoxin participates in many cellular processes including redox signaling, response to oxidative stress and protein reduction (1). A potential role of thioredoxin in human disorders such as cancer, aging and heart disease is currently under investigation (2). Thioredoxin can play a key role in cancer progression, as it acts as a negative regulator of the proapoptotic kinase ASK1 (3) Changes in thioredoxin expression have been associated with meningococcal septic shock and acute lung injury (4,5).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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