2411 EEA1 Antibody #2411

"上海博耀生物销售EEA1 Antibody #2411，CST原装品质，价格优惠，订购EEA1 Antibody #2411，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售EEA1 Antibody #2411，CST原装品质，价格优惠，订购EEA1 Antibody #2411，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：EEA1 Antibody #2411
货号：2411
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2411S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP IF-IC	H M R Mk	Endogenous	170	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： EEA1 Antibody detects endogenous levels of total EEA1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly14 of human EEA1 protein. Antibodies are purified by peptide affinity chromatography.
抗体背景：

EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking (1-2). The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes (3). The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin (4-6). Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion (7).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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