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Phospho-(Thr) MAPK/CDK Substrate Mouse mAb #2321,CST原装品质,价格优惠,订购
Phospho-(Thr) MAPK/CDK Substrate Mouse mAb #2321,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:Phospho-(Thr) MAPK/CDK Substrate Mouse mAb #2321
货号:2321
品牌:CST(cell signaling)
抗体来源:Mouse
克隆类型:
Monoclonal
规格:
| No. |
Size |
Price |
| 2321S |
100 ul (50 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
Isotype |
| W IHC-P E-P |
All |
Endogenous |
Mouse IgM |
Applications Key:
W=Western Blotting
IHC-P=Immunohistochemistry (Paraffin)
E-P=ELISA (Peptide)
Reactivity Key: All=All species expected
Species cross-reactivity is determined by western blot.
特异性/敏感度:
Phospho-(Thr) MAPK/CDK Substrate Mouse mAb detects phospho-threonine only when followed by proline. It reacts with proteins/peptides phosphorylated on the Thr-Pro motif in an otherwise highly context-independent fashion. The antibody does not cross-react with phospho-threonine in the absence of an adjacent proline. The antibody does not cross-react with phospho-tyrosine, but does react with some phospho-serine peptides containing the phospho-serine-proline motif (e.g., phospho-Elk-1). (U.S. Patent No's.: 6,441,140; 6,982,318; 7,259,022; 7,344,714; U.S.S.N. 11,484,485; and all foreign equivalents.)
来源及纯化方法:
Monoclonal antibody is produced by immunizing animals with synthetic phospho-threonine-proline-containing peptides . This antibody is a mouse IgM clone and can be recognized by anti-mouse Ig (whole molecule) secondary antibody. Antibody is purified by protein A chromatography.
抗体背景:
The MAPK and CDK families of serine/threonine protein kinases play
important roles in cell signaling and cell cycle control. These kinases phosphorylate threonine or serine followed by a proline residue (1-6). To study and discover new MAPK and CDK substrates, Cell Signaling Technology has developed antibodies that bind to phospho-threonine followed by proline.
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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