2320 AP-2γ Antibody #2320

"上海博耀生物销售AP-2γ Antibody #2320，CST原装品质，价格优惠，订购AP-2γ Antibody #2320，详情请咨询销售人员！产品详细参

"上海博耀生物销售AP-2γ Antibody #2320，CST原装品质，价格优惠，订购AP-2γ Antibody #2320，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：AP-2γ Antibody #2320
货号：2320
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2320S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IF-IC	H	Endogenous	49	Rabbit

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： AP-2γ Antibody detects endogenous levels of total AP-2γ protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human AP-2γ. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Activator protein 2γ (AP-2γ) is a member of the developmentally-regulated transcription factor activator protein 2 family (1). Overexpression of p53 in human breast cancer cells increases AP-2γ mRNA and protein (2). In addition, p53 binds to the AP-2γ promoter, suggesting that AP-2γ is a target of p53. AP-2γ therefore may contribute to p53-mediated growth inhibition (2). Studies also found that AP-2γ increases p21 mRNA and protein levels and induces cell-cycle arrest in G1 phase (3). Overexpression of AP-2γ inhibits the growth of human breast cancer cells (3). Taken together, these findings suggest that AP-2γ functions as a tumor suppressor (3).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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