2317 S6 Ribosomal Protein (54D2) Mouse mAb #2317

"上海博耀生物销售S6 Ribosomal Protein (54D2) Mouse mAb #2317，CST原装品质，价格优惠，订购S6 Ribosomal Protein (54D2) Mou

"上海博耀生物销售S6 Ribosomal Protein (54D2) Mouse mAb #2317，CST原装品质，价格优惠，订购S6 Ribosomal Protein (54D2) Mouse mAb #2317，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：S6 Ribosomal Protein (54D2) Mouse mAb #2317
货号：2317
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2317S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IF-IC F	H M R Mk Dm	Endogenous	32	Mouse IgG1

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  Dm=D. melanogaster
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： S6 Ribosomal Protein (54D2) Mouse mAb detects endogenous levels of total S6 ribosomal protein independent of phosphorylation.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a recombinant fusion protein corresponding to full-length human S6 ribosomal protein.
抗体背景：

One way that growth factors and mitogens effectively promote sustained cell growth and proliferation is by upregulating mRNA translation (1,2). Growth factors and mitogens induce the activation of p70 S6 kinase and the subsequent phosphorylation of the S6 ribosomal protein. Phosphorylation of S6 ribosomal protein correlates with an increase in translation of mRNA transcripts that contain an oligopyrimidine tract in their 5' untranslated regions (2). These particular mRNA transcripts (5'TOP) encode proteins involved in cell cycle progression, as well as ribosomal proteins and elongation factors necessary for translation (2,3). Important S6 ribosomal protein phosphorylation sites include several residues (Ser235, Ser236, Ser240, and Ser244) located within a small, carboxy-terminal region of the S6 protein (4,5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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