2294 DRAK2 (33D7) Rabbit mAb #2294

"上海博耀生物销售DRAK2 (33D7) Rabbit mAb #2294，CST原装品质，价格优惠，订购DRAK2 (33D7) Rabbit mAb #2294，详情请咨询销售

"上海博耀生物销售DRAK2 (33D7) Rabbit mAb #2294，CST原装品质，价格优惠，订购DRAK2 (33D7) Rabbit mAb #2294，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：DRAK2 (33D7) Rabbit mAb #2294
货号：2294
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2294S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P F	M	Endogenous	43	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  F=Flow Cytometry
Reactivity Key:  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： DRAK2 (33D7) Rabbit mAb detects endogenous levels of total DRAK2 protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surroundingAsp315 of mouse DRAK2.
抗体背景：

DRAK2 (DAP kinase related apoptosis inducing protein kinase 2) is a member of the novel DAP (death associated protein) pro-apoptotic kinase family (1). Overexpression of DRAK2 in NIH/3T3 cells induces morphological changes associated with apoptosis, which are likely to occur in a p53-dependent manner (1,2). DRAK2 is preferentially expressed in lymphoid tissues and regulates the TCR activation threshold during thymocyte selection (3). Indeed, T cells from DRAK2^(-/-) mice exhibit enhanced sensitivity to T cell receptor-mediated stimulation and have a reduced requirement for co-stimulation (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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