产品简介
"上海博耀生物销售Thioredoxin 1 Antibody (Human Specific) #2285,CST原装品质,价格优惠,订购Thioredoxin 1 Antibody (Human
产品说明
"上海博耀生物销售
Thioredoxin 1 Antibody (Human Specific) #2285,CST原装品质,价格优惠,订购
Thioredoxin 1 Antibody (Human Specific) #2285,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:Thioredoxin 1 Antibody (Human Specific) #2285
货号:2285
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2285S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H |
Endogenous |
12 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
Thioredoxin 1 Antibody (human-specific) detects endogenous levels of total human thioredoxin 1 protein.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human thioredoxin 1. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:
Thioredoxin is a small redox protein found in many eukaryotes and prokaryotes. A pair of cysteines within a highly conserved, active site sequence can be oxidized to form a disulfide bond which is then reduced by thioredoxin reductase (1). Multiple forms of thioredoxin have been identified, including cytosolic thioredoxin 1 (Trx1) and mitochondrial thioredoxin 2 (Trx2). Thioredoxin participates in many cellular processes including redox signaling, response to oxidative stress and protein reduction (1). A potential role of thioredoxin in human disorders such as cancer, aging and heart disease is currently under investigation (2). Thioredoxin can play a key role in cancer progression, as it acts as a negative regulator of the proapoptotic kinase ASK1 (3) Changes in thioredoxin expression have been associated with meningococcal septic shock and acute lung injury (4,5).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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