SCD1 (R347) Antibody #2283

"上海博耀生物销售SCD1 (R347) Antibody #2283，CST原装品质，价格优惠，订购SCD1 (R347) Antibody #2283，详情请咨询销售人员！

"上海博耀生物销售SCD1 (R347) Antibody #2283，CST原装品质，价格优惠，订购SCD1 (R347) Antibody #2283，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：SCD1 (R347) Antibody #2283
货号：2283
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2283S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IF-IC	M (H)	Endogenous	37	Rabbit

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： SCD1 (R347) Antibody detects endogenous levels of total SCD1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding R347 of human SCD1. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Stearoyl-CoA desaturase 1 (SCD1) is a key lipogenic enzyme found in the endoplasmic reticulum that catalyzes the conversion of palmitoyl–CoA and stearoyl–CoA to palmitoleoyl–CoA (16:1) and oleoyl–CoA (18:1) (1-3). Palmitoleate and oleate are the major components of triglycerides, membrane phospholipids and cholesterol esters (1). SCD1-knockout mice show improved insulin sensitivity and reduced body fat (1). Disruption of SCD1 in mouse brown adipose tissue strengthens insulin signaling and results in increased translocation of Glut4 to plasma membrane and enhanced uptake of glucose (4). Furthermore, SCD1 is essential for the onset of diet-induced body weight gain (1) and insulin resistance in the liver (5).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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