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2270 MMP-9 (G657) Antibody #2270

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2270

更新时间:2013-07-27

浏览次数:891

公司地址:

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产品简介

"上海博耀生物销售MMP-9 (G657) Antibody #2270,CST原装品质,价格优惠,订购MMP-9 (G657) Antibody #2270,详情请咨询销售人员

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"上海博耀生物销售MMP-9 (G657) Antibody #2270,CST原装品质,价格优惠,订购MMP-9 (G657) Antibody #2270,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:MMP-9 (G657) Antibody #2270
货号:2270
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
2270S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W H Endogenous 92 kDa Rabbit
Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: MMP-9 (G657) Antibody detects full length (proenzyme, 92 kDa) human MMP-9.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to a sequence based around amino acid residue Gly657 of human MMP-9. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:

The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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