2156 Skp1 Antibody #2156

"上海博耀生物销售Skp1 Antibody #2156，CST原装品质，价格优惠，订购Skp1 Antibody #2156，详情请咨询销售人员！产品详细参数如

"上海博耀生物销售Skp1 Antibody #2156，CST原装品质，价格优惠，订购Skp1 Antibody #2156，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Skp1 Antibody #2156
货号：2156
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2156P	40 ul (4 western blots)	询价
2156S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IF-IC F	H M R	Endogenous	19	Rabbit

Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Skp1 Antibody detects endogenous levels of total Skp1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues of human Skp1. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1; the activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2 and then from E2 to ubiquitin ligase E3 for final delivery to the epsilon-NH2 of the target protein lysine residue (1-3). Combinatorial interactions of different E2 and E3 proteins result in substrate specificity (4). Recent data suggest that activated E2 associates transiently with E3, and that the dissociation is a critical step for ubiquitination (5). Skp1 (S phase kinase-associated protein 1) is a critical scaffold protein of the SCF (Skp1/CUL1/F-box) E3 ubiquitin ligase protein complex. Various F-box proteins (e.g. beta-Trcp, Skp2) mediate an interaction to both Skp1, via their defining and conserved domain of 40 amino acids, and to substrates to be ubiquinated (e.g. beta-catenin, p27) (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
Anti-phospho-Tau protein(Ser519)磷酸化微管相关蛋白抗体
Anti-Caspase-9白介素1-β转化酶样凋亡蛋白酶6抗体
Anti-E2F1转录因子E2F-1抗体
ab103247/Anti-Ctip1 antibody
ab101892/Anti-CATSPER4 antibody
Anti-SELS炎症负调控因子蛋白抗体
ab104304/Anti-cPLA2 beta antibody
ab100864/Anti-ACCSL antibody
Anti-GFAP胶质纤维酸性蛋白抗体
Anti-Tau protein微管相关蛋白抗体
ab104298/Anti-ALX4 antibody
Anti-TFF3三叶肽因子3抗体
Anti-IRS-4胰岛素受体底物-4抗体
ab102640/Anti-CHCHD1 antibody
Anti-EphA2/Eph receptor A2内皮细胞受体蛋白酪氨酸激酶抗体
ab102656/Anti-GALR1 antibody"
本页产品地址：http://www.geilan.com/sell/show-3242215.html