2120 FABP4 Antibody #2120

"上海博耀生物销售FABP4 Antibody #2120，CST原装品质，价格优惠，订购FABP4 Antibody #2120，详情请咨询销售人员！产品详细参数

"上海博耀生物销售FABP4 Antibody #2120，CST原装品质，价格优惠，订购FABP4 Antibody #2120，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：FABP4 Antibody #2120
货号：2120
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2120S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	M	Endogenous	15	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： FABP4 Antibody detects endogenous levels of total FABP4 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of mouse FABP4. Antibodies are purified by peptide affinity chromatography.
抗体背景：

Fatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). The predominant fatty acid binding protein found in adipocytes is FABP4, also called adipocyte fatty acid binding protein or aP2. FABP4 is also expressed in macrophages (3). FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes (4). Mice deficient in both FABP4 and ApoE show protection against atherosclerosis when compared with mice deficient only in ApoE (3). Mice carrying a FABP4 genetic variant exhibit both reduced FABP4 expression and a reduced potential for developing type 2 diabetes and coronary heart disease. A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders (1).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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