2109 Src (36D10) Rabbit mAb #2109

"上海博耀生物销售Src (36D10) Rabbit mAb #2109，CST原装品质，价格优惠，订购Src (36D10) Rabbit mAb #2109，详情请咨询销售人

"上海博耀生物销售Src (36D10) Rabbit mAb #2109，CST原装品质，价格优惠，订购Src (36D10) Rabbit mAb #2109，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Src (36D10) Rabbit mAb #2109
货号：2109
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2109S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IHC-F IF-F IF-IC F	H M R Hm Mk B Pg (C)	Endogenous	60	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IHC-F=Immunohistochemistry (Frozen)  IF-F=Immunofluorescence (Frozen)  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat  Hm=Hamster  Mk=Mon key  C=Chicken  B=Bovine  Pg=Pig
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Src (36D10) Rabbit mAb detects endogenous levels of Src proteins. The antibody may cross-react with other Src family members, but does not cross-react with other non-family proteins.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Src.
抗体背景：

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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