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2108 Src Antibody #2108

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2108

更新时间:2013-07-27

浏览次数:844

公司地址:

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产品简介

"上海博耀生物销售Src Antibody #2108,CST原装品质,价格优惠,订购Src Antibody #2108,详情请咨询销售人员!产品详细参数如下

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"上海博耀生物销售Src Antibody #2108,CST原装品质,价格优惠,订购Src Antibody #2108,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:Src Antibody #2108
货号:2108
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Polyclonal
规格:
No. Size Price
2108S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Source
W IP IF-IC F H M R Mk (C) Endogenous 60 Rabbit
Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key  C=Chicken
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: Src Antibody detects endogenous levels of Src proteins. This antibody may cross-react with other Src family members, but does not cross-react with other non-family proteins.
来源及纯化方法: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues close to the carboxy-terminus of human Src. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景:

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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