2107 Non-phospho-Src (Tyr527) Antibody #2107

"上海博耀生物销售Non-phospho-Src (Tyr527) Antibody #2107，CST原装品质，价格优惠，订购Non-phospho-Src (Tyr527) Antibody #

"上海博耀生物销售Non-phospho-Src (Tyr527) Antibody #2107，CST原装品质，价格优惠，订购Non-phospho-Src (Tyr527) Antibody #2107，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Non-phospho-Src (Tyr527) Antibody #2107
货号：2107
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2107P	40 ul (4 western blots)	询价
2107S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M R (C)	Endogenous	60	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  C=Chicken
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Non-phospho-Src (Tyr527) Antibody detects endogenous levels of Src only when dephosphorylated at tyrosine 527. It may also cross-react with Yes, Fyn and Slk based on sequence similarity.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr527 of human Src. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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