2105 Phospho-Src (Tyr527) Antibody #2105

"上海博耀生物销售Phospho-Src (Tyr527) Antibody #2105，CST原装品质，价格优惠，订购Phospho-Src (Tyr527) Antibody #2105，详

"上海博耀生物销售Phospho-Src (Tyr527) Antibody #2105，CST原装品质，价格优惠，订购Phospho-Src (Tyr527) Antibody #2105，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：Phospho-Src (Tyr527) Antibody #2105
货号：2105
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2105P	40 ul (4 western blots)	询价
2105S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IHC-P	H M R (C)	Endogenous	60	Rabbit

Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)
Reactivity Key:  H=Human  M=Mouse  R=Rat  C=Chicken
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： Phospho-Src (Tyr527) Antibody detects endogenous levels of Src only when phosphorylated at Tyr527. The antibody may cross-react with other Src family members such as Yes, Fyn, Fgr and Yrk when phosphorylated at the equivalent sites.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr527 of human Src. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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