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2093 SCF (C19H6) Rabbit mAb #2093

会员指数: 企业认证:

价格:电议

所在地:上海

型号:2093

更新时间:2013-07-27

浏览次数:821

公司地址:

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产品简介

"上海博耀生物销售SCF (C19H6) Rabbit mAb #2093,CST原装品质,价格优惠,订购SCF (C19H6) Rabbit mAb #2093,详情请咨询销售人

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"上海博耀生物销售SCF (C19H6) Rabbit mAb #2093,CST原装品质,价格优惠,订购SCF (C19H6) Rabbit mAb #2093,详情请咨询销售人员!
产品详细参数如下>>>>

产品名称:SCF (C19H6) Rabbit mAb #2093
货号:2093
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型: Monoclonal
规格:
No. Size Price
2093S 100 ul (10 western blots) 询价

抗体应用:
Applications Reactivity Sensitivity MW (kDa) Isotype
W IHC-P F H Endogenous 18 Rabbit
Applications Key:  W=Western Blotting  IHC-P=Immunohistochemistry (Paraffin)  F=Flow Cytometry
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度: SCF (C19H6) Rabbit mAb detects endogenous levels of SCF by immunohistochemical staining and by flow cytometry. Western blotting detects recombinant SCF.
来源及纯化方法: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to amino acids in the N-terminal sequence of human SCF.
抗体背景:

Stem cell factor (SCF) is a growth factor that is essential for hematopoiesis, melanogenesis and fertility. SCF is also known as mast cell growth factor (MCGF), steel factor (SLF), or kit ligand (KL) (1-3). SCF mediates its biological effects by binding to and activating c-Kit (4). SCF induces dimerization of c-Kit followed by trans-autophosphorylation of the cytoplasmic protein tyrosine kinase domain, leading to subsequent recruitment of signaling proteins, tyrosine phosphorylation of substrates and activation of multiple signaling pathways (5,6). SCF/c-Kit may take part in the growth control of human malignancies (7).

关键词:CST,抗体,一抗{byao_back}{byao_back2}

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