产品简介
"上海博耀生物销售CDK7 Antibody #2090,CST原装品质,价格优惠,订购CDK7 Antibody #2090,详情请咨询销售人员!产品详细参数如
产品说明
"上海博耀生物销售
CDK7 Antibody #2090,CST原装品质,价格优惠,订购
CDK7 Antibody #2090,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:CDK7 Antibody #2090
货号:2090
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Polyclonal
规格:
| No. |
Size |
Price |
| 2090S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Source |
| W |
H M R Mk |
Endogenous |
40 |
Rabbit |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
CDK7 Antibody detects endogenous levels of total CDK7 protein.
来源及纯化方法:
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of human CDK7. Antibodies are purified using protein A and peptide affinity chromatography.
抗体背景:
CDK-activating kinase (CAK) is a complex of CDK7 and cyclin H. The complex is involved in cell cycle regulation by phosphorylating an activating residue in the T-loop domain of cdks (1). Regulation of CAK activity is mediated by T-loop phosphorylation and by association with MAT1, both of which enhance its kinase activity toward the CTD of RNA polymerase II (2,3) and other substrates such as p53 (4). CAK is an essential component of the transcription complex TFIIH and may interact directly with TFIIH helicases (5).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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