2085 EGF Receptor (E746-A750del Specific) (6B6) Rabbit mAb #2085

"上海博耀生物销售EGF Receptor (E746-A750del Specific) (6B6) Rabbit mAb #2085，CST原装品质，价格优惠，订购EGF Receptor (E

"上海博耀生物销售EGF Receptor (E746-A750del Specific) (6B6) Rabbit mAb #2085，CST原装品质，价格优惠，订购EGF Receptor (E746-A750del Specific) (6B6) Rabbit mAb #2085，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：EGF Receptor (E746-A750del Specific) (6B6) Rabbit mAb #2085
货号：2085
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Monoclonal
规格：

No.	Size	Price
2085S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IP IHC-P IF-P IF-IC F	H	Endogenous	175	Rabbit IgG

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IF-P=Immunofluorescence (Paraffin)  IF-IC=Immunofluorescence (Immunocytochemistry)  F=Flow Cytometry
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： EGF Receptor (E746-A750del Specific) (6B6) XP^® Rabbit mAb detects endogenous levels of EGFR E746-A750del mutant protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to E746-A750del mutant sequence of human EGFR.
抗体背景：

The epidermal growth factor (EGF) receptor is a 170 kDa transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Research studies have shown that somatic mutations in the tyrosine kinase domain of EGF receptor (EGFR) are present in a subset of lung adenocarinomas that respond to EGFR inhibitors, such as gefinitib and erlotinib (1-3). Two types of mutations account for approximately 90% of mutated cases: a specific point mutation, L858R, that occurs in exon 21 and short in-frame deletions in exon 19 (4,5). The most frequent exon 19 deletion is E746-A750, accounting for 90% of lesions at this site, although some rare variants occur.

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab10062/Anti-GFAP antibody
ab10066/Anti-Fibrinogen antibody
Anti-NGFR/p75NTR神经生长因子受体抗体
ab10323/Anti-CD10 antibody
Anti-MMP-1基质金属蛋白酶-1抗体
ab101923/Anti-GATA5 antibody
ab102587/Anti-Aspartate beta hydroxylase antibody
ab101889/Anti-GRID1 antibody
ab101287/Anti-CCDC50 antibody
ab101368/Anti-Guanylyl Cyclase alpha 1 antibody
ab102614/Anti-C17ORF48 antibody
Anti-Connexin 43间隙连接蛋白43抗体
Anti-Aromatase芳香化酶/细胞色素P450/雌激素合成酶抗体
Anti-DLX4DLX4抗体
Anti-HER4/ErbB4HER4抗体
Anti-VEGF血管内皮生长因子抗体"
本页产品地址：http://www.geilan.com/sell/show-3242156.html