2081 La Antigen Antibody #2081

"上海博耀生物销售La Antigen Antibody #2081，CST原装品质，价格优惠，订购La Antigen Antibody #2081，详情请咨询销售人员！产

"上海博耀生物销售La Antigen Antibody #2081，CST原装品质，价格优惠，订购La Antigen Antibody #2081，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：La Antigen Antibody #2081
货号：2081
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2081S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W IP	H M R Mk	Endogenous	50	Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： La Antigen Antibody detects endogenous levels of total La Antigen protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human La Antigen. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

La antigen is recognized by antibodies in patients with autoimmune disorders such as systemic lupus erythematosus and Sjögren's syndrome (1). La antigen binds to the 5'-noncoding region of poliovirus RNA and is an IRES trans-acting factor (1,2). Depletion of La antigen reduces the function of poliovirus IRES in vivo (3). La antigen, when phosphorylated at Ser366, has been shown to associate with nuclear precursor tRNAs and facilitate their processing (4). The nonphosphorylated La antigen interacts with the mRNAs that have 5'-terminal oligopyrimidine (5'TOP) motifs to control protein synthesis (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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