2076 TMP21 Antibody #2076

"上海博耀生物销售TMP21 Antibody #2076，CST原装品质，价格优惠，订购TMP21 Antibody #2076，详情请咨询销售人员！产品详细参数

"上海博耀生物销售TMP21 Antibody #2076，CST原装品质，价格优惠，订购TMP21 Antibody #2076，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：TMP21 Antibody #2076
货号：2076
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2076S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H M Mk (R)	Endogenous	19	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： TMP21 Antibody detects endogenous levels of total TMP21 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues of human TMP21. Antibodies are purified by protein A and peptide affinity chromatography.
抗体背景：

TMP21, a type I transmembrane protein, is a member of the p24 cargo protein family, which is highly enriched in the ER, the Golgi and coat protein (COP) I and II transport vesicles (1,2). TMP21 is involved in protein transport and vesicular targeting. In particular, TMP21 influences APP trafficking by stabilizing nascent APP. The absence of TMP21 leads to enhanced maturation and cell surface accumulation of APP (3). In addition, TMP21 is a non-essential component of the γ-secretase complex with the potential to modulate γ-secretase mediated cleavage and Aβ production without having an effect on ε-secretase activity (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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