2046 NGF Antibody #2046

"上海博耀生物销售NGF Antibody #2046，CST原装品质，价格优惠，订购NGF Antibody #2046，详情请咨询销售人员！产品详细参数如下

"上海博耀生物销售NGF Antibody #2046，CST原装品质，价格优惠，订购NGF Antibody #2046，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：NGF Antibody #2046
货号：2046
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2046S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H (M)	Recombinant	13	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： NGF Antibody detects recombinant NGF protein. It does not cross-react with other proteins.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Thr146 of human NGF.
抗体背景：

Nerve growth factor (NGF) is a small, secreted protein and member of the neurotrophin family of growth factors that promote neuronal cell survival and differentiation (1). Producing cells release NGF that bind and activate TrkA high affinity receptors to mediate NGF-driven signaling. NGF also binds to a low affinity p75 (NTR) receptors, which belong to the death receptor family (2). Although NGF has been classically described as favoring neuron survival and differentiation, nerve growth factor can promote apoptosis in cells that contain p75 (NTR) and lack TrkA. NGF can induce neuron death in a variety of neurodegenerative conditions, including Alzheimer disease (3). Besides its neurotrophic actions, NGF has an effect on non-neuronal cells and may help mediate inflammation, angiogenesis, and stimulate breast cancer cell growth (4-6). NGF signaling is looking increasingly promising as potential drug targets for diseases.

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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