2029 MCP-1 Antibody (Mouse Specific) #2029

"上海博耀生物销售MCP-1 Antibody (Mouse Specific) #2029，CST原装品质，价格优惠，订购MCP-1 Antibody (Mouse Specific) #2029

"上海博耀生物销售MCP-1 Antibody (Mouse Specific) #2029，CST原装品质，价格优惠，订购MCP-1 Antibody (Mouse Specific) #2029，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：MCP-1 Antibody (Mouse Specific) #2029
货号：2029
品牌：CST(cell signaling)
抗体来源：Rabbit
克隆类型： Polyclonal
规格：

No.	Size	Price
2029S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	M	Endogenous	11-13, 20-30	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： MCP-1 Antibody (Mouse Specific) detects endogenous levels of total mouse MCP-1 protein.
来源及纯化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Cys75 of mouse MCP-1. Antibodies were purified by protein A and peptide affinity chromatography.
抗体背景：

Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, monocyte chemotactic activating factor (MCAF) or glioma-derived chemotactic factor-2 (GDCF-2), is the product of the human JE gene and a member of the family of C-C (or β) chemokines (1-4). The predicted molecular weight of MCP-1 protein is 11-13 kDa, but it may migrate at 20-30 kDa due to glycosylation. MCP-1 is secreted by a variety of cell types in response to pro-inflammatory stimuli and was originally described for its chemotactic activity on monocytes. This activity has led to studies demonstrating its role in diseases characterized by monocyte infiltrates such as psoriasis (5), rheumatoid arthritis (6) and atherosclerosis (7). MCP-1 may also contribute to tumor progression and angiogenesis (8). Signaling by MCP-1 is mediated by the G-protein coupled receptor CCR2 (9).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

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