2014 ZPR1 (LG1) Mouse mAb #2014

"上海博耀生物销售ZPR1 (LG1) Mouse mAb #2014，CST原装品质，价格优惠，订购ZPR1 (LG1) Mouse mAb #2014，详情请咨询销售人员！

"上海博耀生物销售ZPR1 (LG1) Mouse mAb #2014，CST原装品质，价格优惠，订购ZPR1 (LG1) Mouse mAb #2014，详情请咨询销售人员！
产品详细参数如下>>>>

产品名称：ZPR1 (LG1) Mouse mAb #2014
货号：2014
品牌：CST(cell signaling)
抗体来源：Mouse
克隆类型： Monoclonal
规格：

No.	Size	Price
2014S	100 ul (10 western blots)	询价

抗体应用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H M R Mk	Endogenous	51	Mouse IgG1

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Mon key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度： ZPR1 (LG1) Mouse mAb detects endogenous levels of total ZPR1 protein.
来源及纯化方法： Monoclonal antibody is produced by immunizing animals with purified recombinant human ZPR1.
抗体背景：

The zinc finger protein ZPR1 (ZNF259) binds to epidermal growth factor receptor (EGFR) and is localized to both cytoplasm and nucleus. The zinc fingers found in ZPR1 and the tyrosine kinase domain of EGFR mediate the interaction between ZPR1 and the receptor (1). ZPR1 translocates from the cytoplasm to nucleus following mitogen (i.e. EGF) stimulation (2,3). ZPR1 also interacts with translation elongation factor eEF1A in vivo following EGF treatment (3). The interaction between the zinc finger protein and elongation factor is important for cell proliferation. Cells lacking ZPR1 exhibit abnormal nucleolar function, suggesting that ZPR1 is required for cell viability and nucleolar function in dividing cells (3). ZPR1 knockout mice exhibit significant neurodegeneration, and reduced or altered expression of ZPR1 may contribute to spinal muscular atrophy, a disorder characterized by degeneration of spinal cord neurons (4).

关键词：CST，抗体，一抗{byao_back}{byao_back2}

相关产品：
ab102016/Anti-CIDE C antibody
ab101968/Anti-C19orf55 antibody
Anti-Integrin Alpha 3 + Beta 1整合素α3β1抗体(Integrin α3β1)
ab102045/Anti-Glutathione S Transferase theta 2 antibody
Anti-galectin 9半乳糖凝集素9抗体
ab102819/Anti-C1orf41 antibody
ab100876/Anti-Acyl-CoA Thioesterase 9 antibody
Anti-Neurocan神经粘蛋白抗体
ab103213/Anti-AGPAT7 antibody
ab10286/Anti-Calnexin - ER membrane marker antibody
Anti-phospho-Tau protein(Thr529)磷酸化微管相关蛋白抗体
Anti-Nonylphenol壬基酚抗体
ab103231/Anti-CDC45L antibody
Anti-gamma Synuclein核突触蛋白-γ抗体
Anti-DDC/DOPA Decarboxylase多巴胺脱羧酶抗体
Anti-Megsin丝氨酸蛋白酶抑制剂B7抗体"
本页产品地址：http://www.geilan.com/sell/show-3242097.html