产品简介
"上海博耀生物销售eIF4A (C32B4) Rabbit mAb #2013,CST原装品质,价格优惠,订购eIF4A (C32B4) Rabbit mAb #2013,详情请咨询销
产品说明
"上海博耀生物销售
eIF4A (C32B4) Rabbit mAb #2013,CST原装品质,价格优惠,订购
eIF4A (C32B4) Rabbit mAb #2013,详情请咨询销售人员!
产品详细参数如下>>>>
产品名称:eIF4A (C32B4) Rabbit mAb #2013
货号:2013
品牌:CST(cell signaling)
抗体来源:Rabbit
克隆类型:
Monoclonal
规格:
| No. |
Size |
Price |
| 2013P |
40 ul (4 western blots) |
询价 |
| 2013S |
100 ul (10 western blots) |
询价 |
抗体应用:
| Applications |
Reactivity |
Sensitivity |
MW (kDa) |
Isotype |
| W |
H M R Mk |
Endogenous |
48 |
Rabbit IgG |
Applications Key:
W=Western Blotting
Reactivity Key:
H=Human
M=Mouse
R=Rat
Mk=Mon
key
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特异性/敏感度:
eIF4A (C32B4) Rabbit mAb detects endogenous levels of total eIF4A protein.
来源及纯化方法:
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Met316 of human eIF4A protein.
抗体背景:
A variety of factors contribute to the important biological event of initiation of translation. The eIF4F complex of translation initiation factors binds to the 5' m7 GTP cap to open up the mRNA secondary structure and allow small ribosome subunit binding (1). eIF4A, an eIF4 complex component that acts as an ATP-dependent RNA helicase, unwinds the secondary structure of the 5' mRNA untranslated region to mediate ribosome binding (2,3). In addition, eIF4A has recently been shown to repress Dpp/BMP signalling in a translation-independent manner in Drosophila (4,5).
关键词:CST,抗体,一抗{byao_back}{byao_back2}
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