文章资讯：组织因子途径抑制剂抗体

  实验类型：WB,IHC-P,IHC-F,IF,ELISA

  应用范围：Mouse,Rat (predicted: Human,Pig,Cow,Horse,Rabbit)

  注：古朵生物公司产品仅供科研研究实验，不得用于临床!

  商品详情：

  英文名称：TFPI

  中文名称：组织因子途径抑制剂抗体

  别 名;Tissue factor pathway inhibitor; Tissue factor pathway inhibitor-1; convertin; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein associated coagulation inhibitor; TFI; TFPI 1; TFPI1; TFPI1_HUMAN.

  研究领域;心血管

  抗体来源;Rabbit

  克隆类型;Polyclonal

  交叉反应;Mouse, Rat, (predicted: Human, Pig, Cow, Horse, Rabbit, )

  产品应用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

  not yet tested in other applications.

  optimal dilutions/concentrations should be determined by the end user.

  理论分子量;32kDa

  细胞定位;分泌型蛋白

  性 状;Liquid

  浓 度;1mg/ml

  免 疫 原;KLH conjugated synthetic peptide derived from human TFPI: 101-200/304

  亚 型;IgG

  纯化方法;affinity purified by Protein A

  缓 冲 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

  保存条件;Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

  注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

  产品介绍;TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.

  Function:

  Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

  组织因子途径抑制剂抗体 上海古朵生物科技有限公司成立于上海浦东新区。是一家专门从事生物技术相关产品，励志研发和销售的综合性生物公司，产品远销多个国家和地区，我们将一如既往地秉承“一切为了满足客户的需求"的经营宗旨;牢固树立“以客户需求为准则、以市场需求为导向，不断开发高质量的新产品，提供客户满意的综合服务质量"的方针。