JN1379 重组人VEGFR2

我公司致力于为客户提供高纯度、低成本的活性重组蛋白，包括重组人VEGFR2在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。...

特别提示：包括重组人VEGFR2(KDR)(血管内皮生长因子受体2)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人VEGFR2(KDR)(血管内皮生长因子受体2)
英文名称：Recombinant Human Vascular Endothelial Growth Factor Receptor 2
产品货号：JN1379
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala20-Glu764在C端带有Fc标签。

VEGFR2/KDR质量控制：＞95%(还原性SDS-PAGE)

VEGFR2/KDR制剂：冻干品

VEGFR2/KDR保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

VEGFR2/KDR复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于VEGFR2/KDR：
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. It also plays an essential role in promoting proliferation, survival, migration and differentiation of endothelial cells, reorganization of the actin cytoskeleton. VEGFR2 is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo.The adaptor protein SHB has been shown to interact with VEGFR2 in receptor tyrosine kinase signaling. In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposis sarcoma lesions. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

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关注重组人VEGFR2(KDR)(血管内皮生长因子受体2)，重组VEGFR2，rhVEGFR2，重组人血管内皮生长因子受体2，重组血管内皮生长因子受体2，重组Vascular Endothelial Growth Factor Receptor 2，重组人Vascular Endothelial Growth Factor Receptor 2，rKDR，rhKDR，重组KDR，Recombinant Human Vascular Endothelial Growth Factor Receptor 2，rVEGFR2，重组人KDR，重组人VEGFR2的同时，为您推荐更多您可能感兴趣的产品：



名称：重组大鼠血管内皮生长因子A(VEGF-A)(VEGF164)
货号：JN0269
规格：10μg|50μg|500μg|1mg
本品由我们的酵母表达系统制备，目的基因编码的Ala27-Arg190表达纯化而来。

VEGF164质量控制：＞95%(还原性SDS-PAGE)。

VEGF164制剂：冻干品

VEGF164保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

VEGF164复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于VEGF164：
Vascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. VEGF is particularly expressed in supraoptic , paraventricular nuclei and the choroid plexus of the pituitary, and abundant in the corpus luteum of the ovary and in kidney glomeruli. The rat VEGF protein contains a putative 20 amino acids (aa) signal peptide, and alternative splicing of rat VEGF gene produces isoforms of 120, 144, 164 and 188 aa. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. VEGF can bind to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and play important roles in inducing endothelial cell proliferation, promoting cell migration, inhibiting apoptosis and inducing permeabilization of blood vessels.

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