JN1447 重组小鼠ST2(IL-1R4)

产品简介
我公司致力于为客户提供高纯度、低成本的活性重组蛋白,包括重组小鼠ST2(IL-1R4)在内的各类受体、细胞因子、生长因子、转录因子、激素、酶、毒性蛋白、病毒抗原等。...
产品详细介绍
特别提示:包括重组小鼠ST2(IL-1R4)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组小鼠ST2(IL-1R4)
英文名称:Recombinant Mouse Interleukin-1 receptor-like 1
产品货号:JN1447
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser27-Ala337在C端含有His标签。
ST2/IL-1 R4 质量控制:>95%(还原性SDS-PAGE)
ST2/IL-1 R4 制剂:冻干品
ST2/IL-1 R4 保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
ST2/IL-1 R4 复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于ST2/IL-1 R4 :
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.
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